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881.
882.
Sébastien Lacroix Mario Lauria Marie-Pier Scott-Boyer Luca Marchetti Corrado Priami Laura Caberlotto 《Genes & nutrition》2015,10(6)
Worldwide population is aging, and a large part of the growing burden associated with age-related conditions can be prevented or delayed by promoting healthy lifestyle and normalizing metabolic risk factors. However, a better understanding of the pleiotropic effects of available nutritional interventions and their influence on the multiple processes affected by aging is needed to select and implement the most promising actions. New methods of analysis are required to tackle the complexity of the interplay between nutritional interventions and aging, and to make sense of a growing amount of -omics data being produced for this purpose. In this paper, we review how various systems biology-inspired methods of analysis can be applied to the study of the molecular basis of nutritional interventions promoting healthy aging, notably caloric restriction and polyphenol supplementation. We specifically focus on the role that different versions of network analysis, molecular signature identification and multi-omics data integration are playing in elucidating the complex mechanisms underlying nutrition, and provide some examples on how to extend the application of these methods using available microarray data.
Electronic supplementary material
The online version of this article (doi:10.1007/s12263-015-0508-9) contains supplementary material, which is available to authorized users. 相似文献883.
V. Trivellone M. Ripamonti E. Angelini L. Filippin M. Rossi C. Marzachí L. Galetto 《Journal of applied microbiology》2019,127(6):1801-1813
884.
Daniele Arobba Maria Angela Guido Paola Minale Carlo Montanari Sandra Placereani Sabrina Pracilio Costantino Troise Susanna Voltolini Arsenio Corrado Negrini 《Aerobiologia》2000,16(2):233-243
A comparison between two pollen-sampling stationsin the city area of Genoa is presented. The samplingsites are placed 3 km apart, respectively in theeastern urban area (St. Martino Hospital – S.M.) andin the historical centre (Botanical Garden – B.G.).Pollen sampling was carried out during the years1995–1997 at the two different sites by volumetricHirst-type sampler and then compared. The dailyairborne pollen concentration of Urticaceae, Poaceae,Cupressaceae/Taxaceae, Corylaceae/Betulaceae andOleaceae resulted prevailingly higher at S.M., while a good correspondence was observed from a phenologicpoint of view. Asteraceae have shown the bestqualitative-quantitative consistency. In springtime adifference was recorded for Urticales, maybe due tolocal occurence (B.G.) of Broussonetia papyrifera(Moraceae). On the whole, the correspondence betweenthe two different sampling stations proved to besatisfactory. 相似文献
885.
886.